Chlorogenic acid (CGA) is an active component of Yinhua Pinggan Granule, which has antioxidant and anti-inflammatory effects. We chose the CGA to explore its effects on PANoptosis in cultured macrophages infected with CSR-EC. In this study, we explored the protective impact of CGA on macrophage cell damage generated by CSR …
CLAFORAN contains approximately 50.5 mg (2.2 mEq) of sodium per gram of cefotaxime activity. Solutions of CLAFORAN range from very pale yellow to light amber depending on the concentration and the diluent used. The pH of the injectable solutions usually ranges from 5.0 to 7.5. The CAS Registry Number is 6.
Home / Small Molecules / Associated Drug Substance / Cefotaxime Sodium (500 mg) In Stock. Ready to ship. $273.00. star. Part# Product Description 2FC1201 Food Chemicals Codex 12th Edition - Print 3881201 USP Food Chemicals Codex 12th Edition (1st Supplement Only) BOOK ...
cefotaxime decreases effects of sodium picosulfate/magnesium oxide/anhydrous citric acid by altering metabolism. Use Caution/Monitor. Coadministration with antibiotics …
Cefotaxime sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Biochem/physiol Actions Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell ...
Sterile CLAFORAN (cefotaxime sodium) is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration. It is the sodium salt of 7-[2-(2 …
1 g cefotaxime (free acid equivalent) in vials in packages of 10 (NDC 0039-0018-10), packages of 25 ... Cefotaxime sodium overdosage has occurred in patients. Most cases have shown no overt toxicity. The most frequent reactions were elevations of BUN and creatinine. There is a risk of reversible encephalopathy in cases of administration of high ...
Visit ChemicalBook To find more Cefotaxime sodium(6) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical …
Chemsrc provides cefotaxime sodium(CAS#:6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of cefotaxime sodium are included as well.
Generic name: cefotaxime sodium. Dosage form: injection, powder, for solution. Drug class: Third generation cephalosporins. J Code (medical billing code): J0698 (Per 1 g, injection) Medically reviewed by …
This study was conducted after dehydrogenating cefotaxime sodium using 0.75 ml of sodium nitrite and 0.75 ml of hydrochloric acid. The solutions were left on ice for 5 min at 0–5 °C, after which increasing volumes of urea solution (0.25–2.0) were added) ml at a concentration of 1 % to get rid of excess nitrogen gas, then 1 ml of 0.5 % ...
Summary of Use during Lactation . Limited information indicates that cefotaxime produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately …
Sterile Cefotaxime for Injection, USP, is a dry off-white to pale yellow crystalline powder supplied in vials and bottles containing cefotaxime sodium as follows: 500 mg cefotaxime (free acid ... Cockcroft, D.W. and Gault, M.H.: Prediction of Creatinine Clearance from Serum Creatinine, Nephron 16:31-41, 1976.
Cefotaxime is a cephalosporin (SEF a low spor in) antibiotic. Cefotaxime is used to treat many kinds of bacterial infections, including severe or life-threatening forms. …
Cefotaxime using 1, 2-napthaquinone-4-sulfonic acid sodium in bulk and pharmaceutical dosage form CH. Aswani Kumar, T. Anil Kumar, B. M. Gurupadayya*, S. Navya Sloka and M. B.
Antibiotics are commonly used in clinical practice to treat bacterial infections. Due to the abuse of antibiotics, the emergence of drug-resistant strains, such as cefotaxime sodium-resistant Escherichia coli (CSR-EC), has aggravated the treatment of diseases caused by bacterial infections in the clinic. Therefore, discovering new drug …
sodium picosulfate/magnesium oxide/anhydrous citric acid; ticarcillin; voclosporin; warfarin; Cefotaxime has minor interactions with the following drugs: aminohippurate sodium; chloramphenicol; choline magnesium trisalicylate; rose hips ; sulfasalazine; willow bark ; This information does not contain all possible interactions or adverse effects.
Cefotaxime injection may also be used before surgery, and during and after a cesarean section, in order to prevent the patient from getting an infection. Cefotaxime injection is in a class of medications called cephalosporin antibiotics. It works by killing bacteria. Antibiotics such as cefotaxime injection will not work for colds, flu, or ...
748 rowsCefotaxime may decrease the excretion rate of Sodium aurothiomalate …
Cefotaxime for Injection, USP contains approximately 50.5 mg (2.2 mEq) of sodium per gram of cefotaxime activity. Solutions of Cefotaxime for Injection, USP range from very pale yellow to light amber depending on …
2-methoxyiminoacetamido]cephalosporanic acid sodium salt1. Cefotaxime is a broad-spectrum third-generation cephalosporin antibiotic with a wide spectrum of activity. It has particular potency against Gram-negative bacteria such as Enterobacteriaceae, Haemophilus influenzae, Moraxella (Branhamella) catarrhalis, and Neisseria species.
sodium picosulfate/magnesium oxide/anhydrous citric acid. cefotaxime decreases effects of sodium picosulfate/magnesium oxide/anhydrous citric acid by altering metabolism. Use Caution/Monitor. Coadministration with antibiotics decreases efficacy by altering colonic bacterial flora needed to convert sodium picosulfate to active drug.
The values of percentage inhibition efficiency (% IE) and corrosion rate (CR) obtained from weight loss method at different concentrations of cefotaxime sodium in 1 N HCl at 35 °C are summarized in Table 1.The variation of inhibition efficiency with increase in inhibitor concentrations is shown in Fig. 2.It was observed that cefotaxime sodium …
Buy Cefotaxime sodium Ph Eur reference standard for identification, purity tests or assays of pharmaceutical products according to EP monographs. VN EN. ... Cefotaxime acid. View Price and Availability. Sigma-Aldrich. C7912. Cefotaxime sodium salt. View Price and Availability. USP. 1097953.
in which C is the concentration,in mg per mL,of USP Cefotaxime Sodium RS in the Standard preparation, P is the designated content,in µg per mg,of cefotaxime (C 16 H 17 N 5 O 7 S 2)in USP Cefotaxime Sodium RS, W is the weight,in mg,of Cefotaxime Sodium taken to prepare the Assay preparation,and r U and r S are the cefotaxime peak area …
Cefotaxime for injection is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration. It is the sodium salt of 7- [2- (2-amino-4-thiazolyl ... Following IM administration of a single 500 mg or 1 g dose of Cefotaxime to normal volunteers, mean peak serum concentrations of 11.7 and 20.5 mcg/mL respectively were ...
Comparison: cefotaxime sodium CRS. B. It gives reaction (a) of sodium (2.3.1). TESTS Solution S. Dissolve 2.5 g incarbon dioxide-free water R and dilute to 25.0 ml with the same solvent. Appearance ofsolution. SolutionS isclear (2.2.1). Add 1 ml of glacial acetic acid R to 10 ml of solution S. The solution, examined immediately, is clear.
ChEBI: Cefotaxime is a cephalosporin compound having acetoxymethyl and [2- (2-amino-1,3-thiazol-4-yl)-2- (methoxyimino)acetyl]amino side groups. It has a role as a drug allergen and an antibacterial drug. It is a member of 1,3-thiazoles, an oxime O-ether and a cephalosporin. It is a conjugate acid of a cefotaxime (1-).
Cefotaxime. Desacetyl-cefotaxime accounts for 15% to 45% of the peak and 45% to 70% of the trough concentrations of total cefotaxime [417–419]. ... cephalosporanic acid; cefatoxamine; cefotaxime sodium; claforan; hr 756; ru 24756; zariviz; 7 [2 (2 amino 4 thiazolyl) 2 methoxyiminoacetamido]cephalosporanic acid; 7 [2 (2 aminothiazol 4 yl) 2 ...
United States Pharmacopeia (USP) Reference Standard. Synonym (s): Cefotaxime sodium salt, Cefotaxim sodium salt. Empirical Formula (Hill Notation): C16H16N5NaO7S2. CAS Number: 6. Molecular Weight: 477.45.
The Cochrane database of systematic reviews, 8 (8), CD010268-CD010268 () Risk of methicillin-resistant Staphylococcus aureus (MRSA) infection after surgery is generally low, but affects up to 33% of patients after certain types of surgery. Postoperative MRSA infection can occur as surgical site infections (SSIs), chest infections, or ...
Objective: To prepare and validate the chemical structure of the cefotaxime dimer and cefotaxime trimer impurities available from pharmaceutical industry.Methods: A polymer stock solution of cefotaxime sodium was obtained using a concentrated solution degradation method. The cefotaxime dimer and trimer impurities were separated and …
Cefotaxime sodium is a broad-spectrum antibiotic used to treat various bacterial infections. This product is a USP reference standard, which means it meets the highest quality and purity criteria for use in official USP-NF tests and assays. Learn more about its biochem/physiol actions, certificate of analysis and traceability to primary standards.
Among the spectroscopic techniques, 1 H NMR and 13 C NMR elucidated the key functional groups at various chemical shifts while ESI-MS pointed out the molecular weight of cefotaxime sodium in various generations. Similarly, FTIR, DSC, and AFM investigations detailed that the generations are devoid of incompatibilities, structural deformities and ...
Cefotaxime sodium–tazobactam sodium injection (6:1) was well-tolerated at doses of 0.47 to 4.68 g. ... (0.05% acetic acid and 5 mM ammonium acetate). Mass spectrometry was performed using the negative electrospray ionization mode. Analytes were extracted from aliquots of 50.0 μl plasma or urine samples by protein precipitation …
Buy highly pure Cefotaxime Sodium - Impurity G, Mol.Formula : C22H22N8O9S3, Mol.Weight : 638.65, from Pharmaffiliates. Login as registered user for prices, availability and discounts. ... Cefotaxime acid (Y0000420) Cefotaxime sodium (C0685000) Cefotaxime Sodium (IPRS/57/15)-from IPC.
Overview. Cefotaxime sodium is a 3rd Generation Cephalosporin that is FDA approved for the treatment of lower respiratory tract infections, genitourinary infections, gynecologic infections, bacteremia / septicemia, skin and skin structure infections, intra-abdominal infections, bone and/or joint infections and central nervous system infections.
This chapter provides an overview of cefotaxime. It discusses the nomenclature, formula, molecular weight, and appearance, color, odor, and taste of cefotaxime. Various physical properties—solubility, moisture content, pH range, optical rotation, and spectral properties—are discussed. Cefotaxime is a semisynthetic …
Cefotaxime. Sharon S. Castle, in xPharm: The Comprehensive Pharmacology Reference, 2007 Therapeutics. Cefotaxime is active against gram-positive organisms and a wide range of gram-negative organisms, excluding pseudomonas. Staphylococcal coverage lessens in this third-generation group. Cefotaxime is used for the treatment of meningitis, lower …